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The monomeric oligomeric states of DDR
2020-07-28
The monomeric/oligomeric states of DDR2-V5-His and DDR2-Fc were confirmed by Western blotting under reducing and non-reducing conditions. As shown in Fig. 1b, DDR2-V5-His exhibited a relative molecular mass of ~60 kDa under both reducing and non-reducing conditions, consistent with this protein bein
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br Conclusions br Acknowledgements The authors wish
2020-07-28
Conclusions Acknowledgements The authors wish to thank BP International Limited (UK), Statoil (Norway), and Petrobras (Brazil) for supporting this work as part of the CHIGP project (Chemicals in Gas Processing). We wish to thank particularly BP for input and many exciting discussions. Intro
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br Results and discussion br Conclusions The
2020-07-28
Results and discussion Conclusions The results of KKR and KKR-CPA electronic structure calculations were presented for LiMO2 compounds and LiNiCoMn0.1O2 solid solutions, respectively. It was found that Mn impurity located in semiconducting LiCoO2 matrix might exhibit magnetic moment. The mixin
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(R)-PFI 2 hydrochloride australia Cellular senescence is a p
2020-07-28
Cellular senescence is a permanent (R)-PFI 2 hydrochloride australia and proliferative arrest, triggered by telomere attrition, DNA damage, and genomic and proteomic instability that plays a role in several complex biological processes, such as development, tissue repair, aging, and age-related dis
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The development and physiology of cartilage
2020-07-28
The development and physiology of cartilage and bones are highly similar in mammals and teleosts validating the zebrafish as a reliable vertebrate model in this field [22]. Expression of genes and the molecular pathways involved in the endochondral ossification are well conserved. For instance, as i
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Methamphetamine can undergo many derivatisation reactions in
2020-07-28
Methamphetamine can undergo many derivatisation reactions, including silylation, acylation, carbamate formation and Schiff selonsertib formation; however, many of these are not feasible for on-sorbent derivatisation as they require strict reaction conditions such as high temperatures or the total ab
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While a number of studies have
2020-07-27
While a number of studies have helped elucidate the principles of target amino group specificity, UBL selectivity, and Ub mps1 specificity [3], [4], [9], [10], [14], [19], [20], [23], [24], [33], [34], [37], [38], [39], [40], [41], the role of the canonical E2-RING interface in governing substrate
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The present work lays the groundwork for reactor
2020-07-27
The present work lays the groundwork for reactor engineering, required for proper scaling of synthesis. An enzyme’s kinetic mechanism (the order and manner of substrate binding and product release) determines its kinetic rate law. The rate law defines the turnover rate as a function of substrate con
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br MCADD review br Funding None br Introduction
2020-07-27
MCADD review Funding None. Introduction Bacteroides species are obligate anaerobes, Gram-negative, and non-spore-forming bacteria and 21 species of this genus are found particularly in the oral cavity and gastrointestinal tract in vertebrates [1,2]. B. fragilis is the most common papain p
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P has three subfamilies CYP CYP and CYP which
2020-07-27
P450 has three subfamilies (CYP1, CYP2, and CYP3), which contribute largely to the oxidative biotransformation of xenobiotics that include most drugs, dietary chemicals, and environmental pollutants. The CYP1 enzymes have great importance in the bioactivation of mutagens and its isoforms are capable
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We also identified a role for
2020-07-27
We also identified a role for the transcription factor p53 in the regulation of the Crm1 promoter. p53 can activate or repress the transcription of target genes. While activation generally occurs through binding of p53 to its consensus binding site in the promoter region of target genes, for example
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In our previous study intracerebroventricular
2020-07-27
In our previous study, intracerebroventricular-administered urocortin-2 enhanced a conditioned freezing fear response and significantly decreased rat exploratory activity in the open field test [9]. Exogenous urocortin-2 enhanced the conditioned fear-induced expression of c-Fos in the central amygda
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Although the relationship between central and peripheral
2020-07-27
Although the relationship between central and peripheral regulation of CRF signaling is yet to be elucidated, an accumulation of findings indicates independent regulation between central and peripheral CRF signaling. For example, i.c.v. administration of CRF to hypophysectomized rats induced locomot
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Structural comparison of PcP H with PPHD and
2020-07-27
Structural comparison of PcP4H1 with PPHD and human HIF1α-PHD2 reveals that DSBH core fold, Fe2+ and 2-oxoglutarate cid calculator are all conserved. The low affinity of PcP4H1 for 2-oxyglutarate (550 mM) relative to the K value of 2-oxoglutarate for PPHD (400 μM) [13] suggests that other molecules
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Characterization factor is another variable suggested in
2020-07-25
Characterization factor is another variable suggested in the presented correlation. Specific gravity (SG) and normal boiling point of hydrocarbons are needed to calculate Watson characterization factor [61], [62]: The boiling point of bitumen cannot be precisely measured, because bitumens contain
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