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For immobilization of enzymes natural polymers depict severa
2019-12-05
For immobilization of enzymes, natural polymers depict several outstanding features as support. These materials are inert, non-toxic, biodegradable and biocompatible. As well as, they can be treated with different functional groups easily by chemical reactions that occur under gentle conditions in a
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The different serotypes A G have unique receptors to
2019-12-05
The different serotypes (A-G) have unique receptors to which they bind to produce the toxic effect on the nerve cells. (Lance, 2004, Rosetto et al., 2014). Intracellularly, the endopeptidase activity of different serotypes of BoNT target selectively a unique group of proteins, the SNARE hyPerFUsion™
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Eggs have been recognized as an important contributor
2019-12-05
Eggs have been recognized as an important contributor of functional ingredients for humans [3]. Egg yolk is composed of various biologically active proteins. The water-soluble proteins of egg yolk have been examined for their functional effects on longitudinal bone growth during the growth period in
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Although shoulder dub off on
2019-12-05
Although shoulder dub-off on gun drills has significant influence on chip transportation behavior, most commercial gun drills adhere to a fixed design of 20° that has limited scientific basis. To determine the effects of shoulder dub-off on chip evacuation, 5 different angles ranging from 0° to 30°
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ICT is a product of icariin via
2019-12-04
ICT is a product of icariin via the metabolism of intestinal bacteria with estrogen-like activities [33]. ICT as a bone-protecting agent can enhance osteoblast differentiation while suppressing osteoclastic differentiation in vitro [19], and stimulate osteogenic differentiation and inhibit adipogen
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Acknowledgments We acknowledge the Danish Council for Indepe
2019-12-04
Acknowledgments We acknowledge the Danish Council for Independent Research (Grant no. 11-105250) and the Carlsberg Foundation (Grant no. 2011-01-0567) for funding this work. Introduction DNA is vital as a biological target to design diagnostic agents as well as therapeutic drugs. The recognitio
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Thiamet G sale In conclusion DDR ECD was shown to be
2019-12-04
In conclusion, DDR1 ECD was shown to be sufficient for collagen mediated DDR1 oligomerization, and the oligomerized form binds to collagen with increased affinity. In full length receptors expressed on live cells, DDR1 oligomerization occurred on the cell surface in agreement with the role of DDR1 E
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Introduction Tumor necrosis factor TNF is a pro inflammatory
2019-12-04
Introduction Tumor necrosis factor (TNF) is a pro-inflammatory mediator with the capacity to induce apoptosis (Benderska et al., 2012). Recent reports have shown that TNF might trigger cell death, at least in part, by directly affecting the reorganization of the FTY720 Phosphate cytoskeleton (Camp
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HvPap a member of the
2019-12-04
HvPap-1, a member of the cathepsin F-like family, was identified in germinating barley seeds (Sreenivasulu et al., 2008). This enzyme participates in the mobilization of stored proteins (mainly hordeins) during the last phase of grain germination, and its activity is modulated by a propeptide or/and
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Magnetic interactions between metal ions are usually describ
2019-12-04
Magnetic interactions between metal ions are usually described by superexchange via intermediate ligands. Although the general principles of the superexchange mechanism are essentially the same for d and f ions, calculations of exchange parameters for lanthanides are more difficult than for transiti
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Given that dimethylamine substitution was tolerated as in SR
2019-12-04
Given that dimethylamine substitution was tolerated as in SR106447 (), we investigated NHS-12-Biotin amine substitutions as replacements for the -butyl group (). Cyclic amines (SR19880, 19882) or simple mono-substituted anilines (SR20037) were not active, nor was an acetylated version (SR20039). Th
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Recent studies investigating the effects of mesenchymal stem
2019-12-03
Recent studies investigating the effects of mesenchymal stem cell (MSC) therapy in rodent models including chronic renal failure and glomerulonephritis have demonstrated that MSC therapy can result in beneficial effects [57], [58]. In cats, autologous intra-renal injections of either adipose tissue-
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Although MMP might be a downstream target of
2019-12-03
Although MMP-9 might be a downstream target of Src kinase signaling (Liu and Sharp, 2011), a direct connection has not been established. We showed for the first time that, in the collagenase-induced ICH model, Src kinase signaling regulates MMP-9 activity and mediates EP1R toxicity. Consistent with
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br Materials and methods br
2019-12-03
Materials and methods Results Discussion Inflammatory signalling and in particular the arachidonic Nifedipine cascade have been suggested as targets for disease modification, optimization of the therapeutic response, and even restoration of pharmacosensitivity (Potschka, 2010). Recently, w
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Zalcitabine Developmental relationships between CD bright an
2019-12-03
Developmental relationships between CD56bright and CD56dim NK Zalcitabine remain unresolved; however, several studies indicate that the former is a precursor of the latter. An NK subset with intermediate features between CD56bright and CD56dim has been identified, corroborating this developmental tr
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